Table of Contents > Drug > Sargramostim Print



Related terms
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    Related terms
    • Brand Names: U.S.: Leukine®
    • Brand Names: Canada: Leukine®

    • It is used to treat cancer patients who have had bone marrow problems caused by chemo.
    • It is used to treat low white blood cell counts.
    • Sargramostim helps make white blood cells in the bone marrow.


    How to take

    • It is given as a shot into the fatty part of the skin.
    • It is given into a vein for a period of time.

    Missed Dose

    • Call your doctor for an office visit.



    • If you have an allergy to sargramostim or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • Do not get this drug on the same day that you are getting chemo or radiation.


    • If you have lung disease, talk with your doctor.
    • If you have a weak heart, talk with your doctor.
    • Have your blood work checked. The dose of this drug may be changed depending on the results. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Irritation where the shot is given.
    • Headache.
    • Fever and chills.
    • Not able to sleep.
    • Swelling in the feet or hands.
    • Bone pain. You may be given drugs before this shot to avoid these signs.
    • Aches and pains. Mild pain drugs may help.
    • Feeling tired or weak.
    • High blood pressure.
    • Loose stools (diarrhea).
    • Low blood pressure, a fast heartbeat, flushing, and passing out may rarely happen with the first dose.
    • Unsafe allergic effects may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • A fast heartbeat.
    • Trouble breathing.
    • Very bad dizziness or passing out.
    • Very loose stools (diarrhea).
    • Swelling in your legs or belly.
    • A big weight gain.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
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    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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