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Progesterone

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Crinone®;Endometrin®;FirstT-Progesterone VGS 100;FirstT-Progesterone VGS 200;FirstT-Progesterone VGS 25;FirstT-Progesterone VGS 400;FirstT-Progesterone VGS 50;Prometrium®
    • Brand Names: Canada: Crinone®;Prometrium®

    Uses
    • It is used in in vitro fertilization.
    • It is used to stop endometrial changes in women after change of life who are getting estrogen therapy.
    • It is used to treat uterine bleeding due to hormonal imbalance.
    • It is used to treat endometriosis.
    • It is used to treat women who do not have a monthly period cycle.
    • Progestins are made by the body and are used by the milk-making glands and to help the period (menstrual) cycle.
    • It helps with pregnancy.

    Dosing

    How to take

    • Capsule:
    • Follow how to use as you have been told by your doctor or read the package insert.
    • Take with or without food. Take with food if it causes an upset stomach.
    • Shot:
    • It is given as a shot into a muscle.
    • Vaginal:
    • Use gel vaginally.
    • Use tablet vaginally.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store at room temperature.
    • Protect capsules from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Do not take with estrogens to stop heart disease or dementia. Using estrogens may raise your chances of having a heart attack, a stroke, breast cancer, or a blood clot.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

    Avoid

    • If you have an allergy to progesterone or any other part of this drug.
    • If you have a peanut allergy and are taking the capsules. The capsules have peanut oil in them.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Bleeding into the brain, blood clots, breast cancer, heart attack, liver disease, stroke, or vaginal bleeding.
    • Capsule:
    • If you are pregnant or may be pregnant.

    Precautions

    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • If you have an allergy to any type of nuts or seeds, talk with your doctor. Some products have nuts in them.
    • If you have any blood flow problems, talk with your doctor.
    • If you have heart disease, talk with your doctor.
    • Do not take St John's wort with this drug. This drug may not work as well.
    • Do not take other vaginal drugs within 6 hours of this drug.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Periodic breast (monthly self-exam) and regular breast and gynecologic exams are major.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Headache.
    • Belly pain.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Enlarged breasts.
    • Breast pain.
    • Muscle pain.
    • Joint pain.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
    • Chest pain or pressure.
    • Trouble breathing.
    • Swelling, warmth, or pain in the leg or arm.
    • Change in thinking clearly and with logic.
    • Sudden change in eyesight, eye pain, or irritation.
    • Any rash.
    • For women, period changes. These include lots of bleeding, spotting, or bleeding between cycles.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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