Table of Contents > Drug > Pramlintide Print

Pramlintide

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: SymlinPen®;Symlin® [DSC]

    Uses
    • It is used to lower blood sugar in patients with high blood sugar (diabetes).
    • Pramlintide works like amylin, a hormone needed for the body's use of food. Type 1 diabetics have no amylin of their own. Type 2 diabetics still make amylin, but may need more.

    Dosing

    How to take

    • Use as you have been told, even if you are feeling better.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.
    • Give this drug at some other site from where you gave your insulin if you are also getting insulin.
    • Do not mix this drug in the same syringe with insulin.
    • Follow the diet and workout plan that your doctor told you about.
    • It is given as a shot right before a meal into the fatty part of the skin.
    • You may need to lower the dose of insulin you take, talk with your doctor.

    Missed Dose

    • Never make up a missed dose. Skip the missed dose and go back to your normal time.
    • If it is close to the time for the next dose and you have already eaten, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • If you stop taking this drug, talk with your doctor. You may need to be restarted at a lower dose and raise the dose slowly.

    Storage

    • Store unopened vials and pens in a refrigerator. Do not freeze.
    • Store opened vials and pens at room temperature or in a refrigerator. Throw away any part not used after 1 month.
    • Protect opened vials and pens from heat.
    • Protect vials and pens from light.

    Safety



    Warnings

    • Unsafe low blood sugar may happen when taking this drug with your insulin. Do not drive or use heavy machinery until you know the effects of this drug on your blood sugar.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to pramlintide or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have slow stomach clearing.
    • If you cannot tell when your blood sugar is low.

    Precautions

    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not run out of this drug.
    • Wear disease medical alert ID (identification).
    • If you are 80 or older, use this drug with care. You could be more sensitive to low blood sugar.
    • Check your blood sugar as you have been told by your doctor.
    • Tell your doctor if you have had repeated low blood sugar or if you cannot feel or do not know the signs of very low blood sugar.
    • Have your blood work checked often. Talk with your doctor.
    • Have an eye exam and visit the foot doctor every year.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell your doctor if you are taking any other drugs to speed up food clearing from your stomach.
    • Do not drive if your blood sugar has been low. There is a greater chance of you having a crash.
    • Limit your drinking of wine, beer, or mixed drinks.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Low blood sugar. Signs include anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.
    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. This may get better once you are on a stable dose of this drug.
    • Weight loss.
    • Not hungry.
    • Irritation where the shot is given.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Very upset stomach or throwing up.
    • Very low blood sugar or very high blood sugar.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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