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Polymyxin B


Related terms
Author information


    Related terms

      • It is used to treat bacterial infections.
      • Polymyxin B works to harm the bacteria and fight the infection.


      How to take

      • It is given as a shot into a muscle or vein.
      • It is given into the spine.
      • It is given into the bladder as a wash sometimes.
      • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

      Missed Dose

      • Call your doctor to find out what to do.


      • This drug will be given to you in a hospital or doctor's office. You will not store it at home.



      • This drug has not been fully studied in pregnant women. Talk with your doctor.
      • Shot: May cause kidney function to get worse and cause trouble breathing, and it may change your sense of balance.


      • If you have an allergy to polymyxin B or any other part of this drug.
      • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.


      • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
      • If you have kidney disease, talk with your doctor.
      • If you have myasthenia gravis, talk with your doctor.
      • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
      • Tell your doctor if you are pregnant or plan on getting pregnant.
      • Tell your doctor if you are breast-feeding.

      Side Effects

      • Irritation where the shot is given.
      • Kidney function that gets worse.
      • Allergic side effects may rarely happen.


      • Change in the health problem being treated. Is it better, worse, or about the same?

      Contact a healthcare provider

      • If you think there was an overdose, call your local poison control center or ER right away.
      • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
      • Trouble breathing.
      • Big change in balance.
      • Very loose stools (diarrhea), even after drug is stopped.
      • Change in hearing.
      • Feeling very tired or weak.
      • Very nervous and excitable.
      • Numbness or tingling in your hands or feet.
      • Not able to pass urine.
      • Sudden change in eyesight, eye pain, or irritation.
      • Any rash.
      • Side effect or health problem is not better or you are feeling worse.

      General Statements

      • If you have a very bad allergy, wear an allergy ID at all times.
      • Do not share your drugs with others and do not take anyone else's drugs.
      • Keep all drugs out of the reach of children and pets.
      • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
      • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
      • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
      • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
      • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

      Author information
      • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

      Copyright © 2011 Natural Standard (

      The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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