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Pegvisomant

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Somavert®
    • Brand Names: Canada: Somavert®

    Uses
    • It is used to treat acromegaly.
    • Pegvisomant blocks the effect of growth hormone in your body.

    Dosing

    How to take

    • Use as you have been told, even if you are feeling better.
    • It is given as a shot into the fatty part of the skin.
    • Your doctor may teach you how to give the shot.
    • Wash your hands before and after use.
    • Move the site where you give the shot with each shot.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store unopened vials in a refrigerator. Do not freeze.
    • Once mixed, use right away. You may keep at room temperature for up to 6 hours.

    Safety



    Avoid

    • If you have an allergy to pegvisomant or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have a latex allergy, talk with your doctor.

    Precautions

    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • If you have high blood sugar (diabetes), talk with your doctor. This drug may lower blood sugar. High blood sugar drugs may need to be changed.
    • If you have high blood pressure, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • Have your blood pressure and heart rate checked often. Talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • High blood pressure.
    • Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea).
    • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
    • Irritation where the shot is given.
    • Harm to the liver may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness.
    • Big change in balance.
    • Change in thinking clearly and with logic.
    • Very upset stomach or throwing up.
    • Dark urine or yellow skin or eyes.
    • Feeling very tired or weak.
    • Not able to eat.
    • Very bad skin irritation.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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