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Pegfilgrastim

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Neulasta®
    • Brand Names: Canada: Neulasta®

    Uses
    • It is used to lower the chance of getting an infection in cancer patients who have had very bad bone marrow problems caused by chemo.
    • Pegfilgrastim helps make white blood cells in the bone marrow.

    Dosing

    How to take

    • It is given as a shot into the fatty part of the skin.
    • Your doctor may teach you how to give the shot.
    • Before giving the shot, bring it to room temperature.
    • Wash your hands before and after use.
    • Throw syringe away after use. Do not use more than one time.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store in a refrigerator. Do not freeze.
    • You may store at room temperature for 2 days.
    • Protect from light.

    Safety



    Avoid

    • If you have an allergy to pegfilgrastim, filgrastim, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have a latex allergy, talk with your doctor.
    • Do not get this drug on the same day that you are getting chemo or radiation.

    Precautions

    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • If you have sickle cell disease, talk with your doctor.
    • If you weigh less than 99 pounds (45 kilograms), talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Bone pain.
    • Headache.
    • Swelling in the arms or legs.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Unsafe allergic effects may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • A fast heartbeat.
    • Very bad dizziness or passing out.
    • Trouble breathing.
    • Very bad belly pain.
    • Very bad shoulder pain.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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