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Related terms
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    Related terms
    • Brand Names: U.S.: SandoSTATIN LAR®;SandoSTATIN®
    • Brand Names: Canada: Octreotide Acetate Injection;Octreotide Acetate Omega;Sandostatin LAR®;Sandostatin®

    • It is used to treat loose stools (diarrhea) and flushing caused by cancer.
    • It is used to treat some causes of very loose stools (diarrhea).
    • It is used to treat acromegaly.
    • It is used to treat bleeding from esophageal varices in cirrhosis.
    • It is used to treat high insulin levels.
    • It is used to treat an overdose caused by drugs that treat high blood sugar (diabetes).
    • It is used to help GI (gastrointestinal) tract openings close.
    • It is used to treat too much growth hormone release.
    • It is used to treat GI (gastrointestinal) bleeding.
    • Octreotide is a hormone in the body.
    • It lowers how much growth hormone is made by your body.
    • It lowers insulin levels.
    • It slows movement in the GI (gastrointestinal) tract by letting more water get into it.


    How to take

    • All products:
    • Wash your hands before and after use.
    • Follow how to give closely if you or a family member is giving the shot at home.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.
    • Sandostatin®:
    • It is given as a shot into the fatty part of the skin.
    • Move the site where you give the shot with each shot.
    • Esophageal bleeding: This drug is given into a vein for a period of time.
    • Sandostatin LAR®:
    • It is given as a shot into a muscle once a month.

    Missed Dose

    • If drug is given at home:
    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.
    • If this drug is given by your doctor:
    • Call your doctor for an office visit.


    • Sandostatin®:
    • Store unopened vials in a refrigerator or at room temperature. If stored at room temperature, throw away after 2 weeks.
    • Protect from light.
    • Use right after opening.



    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to octreotide or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.


    • If you have high blood sugar (diabetes), talk with your doctor.
    • If you have gallbladder disease, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have a slow heartbeat, talk with your doctor.
    • If you have thyroid disease, talk with your doctor.
    • If you have a weak heart, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check your blood sugar as you have been told by your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Belly pain.
    • Gas.
    • Hair loss. Hair most often grows back when this drug is stopped.
    • Itching.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Short-term pain after use.
    • High blood pressure.
    • High blood sugar. This most often goes back to normal when drug is stopped.
    • Low blood sugar. Signs include anger, shaking, a fast heartbeat, confusion, or sweating. Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.
    • Slow heartbeat.
    • Acromegaly: Loose stools (diarrhea).
    • Gallstones may rarely happen.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Flu-like signs. These include headache, weakness, fever, shakes, aches, pains, and sweating. Mild pain drugs may help.
    • Feeling tired or weak.
    • Headache.
    • Irritation where the shot is given.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain or pressure.
    • Very upset stomach or throwing up.
    • Very low blood sugar or very high blood sugar.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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