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Nafarelin

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Synarel®
    • Brand Names: Canada: Synarel®

    Uses
    • It is used to treat endometriosis.
    • It is used to delay puberty in children who are maturing too early.
    • Nafarelin lowers hormone levels.
    • It lowers estrogen levels in women.
    • It lowers testosterone levels in men.

    Dosing

    How to take

    • To gain the most benefit, do not miss doses.
    • Use as you have been told, even if you are feeling better.
    • Do not take this drug by mouth. Use in your nose only. Keep out of your mouth and eyes (may burn).
    • Blow your nose before use.
    • Do not sneeze during or right after using this drug.
    • Check your spray use with your doctor at each visit. Read and follow the facts on how to use the spray. Make sure you use the spray the right way.

    Missed Dose

    • Use a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not use 2 doses or extra doses.

    Storage

    • Store at room temperature.
    • Protect from light.

    Safety



    Avoid

    • If you have an allergy to nafarelin or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have vaginal bleeding and have not been to your doctor.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • Use care if you have risks for heart disease (high blood pressure, high cholesterol, overweight, high blood sugar (diabetes), cigarette smoking, man older than 40 years of age, other family members with early heart disease, woman after change of life). Talk with your doctor.
    • If you have soft, brittle bones (osteoporosis), talk with your doctor.
    • Use care if you have risks for soft, brittle bones called osteoporosis (alcohol use, cigarette smoking, other family members with brittle bones, taking drugs to treat seizures, taking steroids).
    • Have a bone density test if you are taking this drug for more than 6 months or if you have risks for soft, brittle bones (osteoporosis).
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not use a nose decongestant spray within 2 hours after using this drug.
    • Birth control pills and other hormone-based birth control may not work to stop pregnancy. Use 2 kinds of birth control while taking this drug.

    Side Effects

    • Headache.
    • Flushing. Wearing layers of clothes or summer clothes and staying in cool places may help.
    • Pimples (acne).
    • Vaginal irritation.
    • Nose irritation.
    • Runny nose.
    • Weak bones with long-term use.
    • Emotional ups and downs.
    • Mood changes.
    • Change in sex ability. This most often goes back to normal.
    • Ovarian cysts may rarely happen in the first 2 months of therapy.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain or pressure.
    • Very upset stomach or throwing up.
    • Bad nose irritation.
    • Very bad headache.
    • Sudden change in eyesight, eye pain, or irritation.
    • Change in thinking clearly and with logic.
    • For women, still having a period.
    • For women, if you get pregnant while taking this drug.
    • More trips to the bathroom, more thirst, or weight loss.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.
    • Read the package insert for more details.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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