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Mesna

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Mesnex®
    • Brand Names: Canada: Mesna for injection;Uromitexan

    Uses
    • It is used to lower the bad effects of some cancer drugs on the bladder.
    • Mesna binds with some cancer drugs in the bladder to lower their harmful effects.

    Dosing

    How to take

    • It may be taken by mouth.
    • It may be mixed with water, milk, juice, or a carbonated drink.
    • It may be given as a shot.
    • This drug is given with your cancer drugs.
    • It may be given with your cancer drug and for 2 or more extra doses.
    • This drug must be taken exactly as you have been told.
    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • Do not take 2 doses at the same time or extra doses.
    • Call your doctor to find out what to do.

    Storage

    • Store at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.

    Safety



    Avoid

    • If you have an allergy to mesna or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

    Precautions

    • If you have kidney disease, talk with your doctor.
    • If you have an autoimmune disease such as rheumatoid arthritis or lupus, talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Bad taste in your mouth. This most often goes back to normal.
    • Loose stools (diarrhea).
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Belly pain.
    • Cough.
    • Irritation where the shot is given.

    Contact a healthcare provider

    • Tell your doctor if you throw up within 2 hours of taking the oral drug. The dose may need to be repeated.
    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Blood in the urine.
    • Not able to pass urine.
    • Any bruising or bleeding.
    • Very bad dizziness or passing out.
    • Very loose stools (diarrhea).
    • Very upset stomach or throwing up.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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