Table of Contents > Drug > Lopinavir and Ritonavir Print

Lopinavir and Ritonavir

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Kaletra®
    • Brand Names: Canada: Kaletra®

    Uses
    • It is used to treat HIV infection.
    • Lopinavir works to harm the virus and fight the infection.
    • Ritonavir raises the levels of lopinavir in the blood.

    Dosing

    How to take

    • To gain the most benefit, do not miss doses.
    • Swallow tablet whole. Do not chew, break, or crush.
    • There is a liquid (solution) if you cannot swallow pills.
    • Take liquid with food; tablets may be taken with or without food.
    • Those who have feeding tubes may also use the liquid. Flush the feeding tube before and after this drug is given.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store tablets at room temperature.
    • Protect tablets from water. Do not store in a bathroom or kitchen.
    • Store liquid (solution) in a refrigerator or at room temperature. If stored at room temperature, throw away any part not used after 2 months.
    • Protect solution from heat.

    Safety



    Warnings

    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to lopinavir, ritonavir, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

    Precautions

    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not run out of this drug.
    • If you have high blood sugar (diabetes), talk with your doctor. This drug may raise blood sugar.
    • If you have heart disease, talk with your doctor.
    • If you have hemophilia, talk with your doctor.
    • If you have high cholesterol, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have had an irritated pancreas, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • To protect from diseases caused by having sex, use a latex condom.
    • Use birth control that you can trust to stop pregnancy in HIV disease.
    • Do not use a hormone-related kind of birth control.
    • Do not breast-feed if you have HIV disease and live in the U.S.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • High cholesterol level.
    • High triglyceride level.
    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Belly pain.
    • Loose stools (diarrhea).
    • Change in body fat.
    • Feeling tired or weak.
    • Harm to the liver may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad belly pain.
    • A fast heartbeat.
    • Very bad dizziness or passing out.
    • Very upset stomach or throwing up.
    • More trips to the bathroom, more thirst, or weight loss.
    • Dark urine or yellow skin or eyes.
    • Not able to eat.
    • Feeling very tired or weak.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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