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Letrozole

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Femara®
    • Brand Names: Canada: Femara®;JAMP-Letrozole;Letrozole Tablets, USP;MED-Letrozole;Myl-Letrozole;PMS-Letrozole;Sandoz-Letrozole

    Uses
    • It is used to treat breast cancer in women after change of life.
    • Letrozole lowers estrogens in the body. In breast cancer, growth of the cancer may be fueled by estrogens.

    Dosing

    How to take

    • Take this drug at the same time of day.
    • Take with or without food. Take with food if it causes an upset stomach.
    • This drug works best when used with calcium/vitamin D and weight-bearing workouts like walking or PT (physical therapy).
    • Follow the diet and workout plan that your doctor told you about.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store at room temperature.
    • Protect from light.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Avoid

    • If you have an allergy to letrozole or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have not stopped your period.
    • If you are pregnant or may be pregnant.

    Precautions

    • If you have high blood pressure, talk with your doctor.
    • If you have high cholesterol, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have soft, brittle bones (osteoporosis), talk with your doctor.
    • Have a bone density test. Talk with your doctor.
    • Have your blood pressure and heart rate checked often. Talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.

    Side Effects

    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Feeling tired or weak.
    • Flushing. Wearing layers of clothes or summer clothes and staying in cool places may help.
    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Cough.
    • Back pain.
    • Muscle pain.
    • Swelling.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Bone pain.
    • Brittle bones.
    • High cholesterol level.
    • Weight gain.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain or pressure, a fast heartbeat, or passing out.
    • Trouble breathing.
    • Shortness of breath.
    • Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
    • A big weight loss.
    • Swelling, warmth, or pain in the leg or arm.
    • Very bad headache.
    • Feeling very tired or weak.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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