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    Related terms
    • Brand Names: U.S.: Remicade®
    • Brand Names: Canada: Remicade®

    • It is used to lower drainage from holes in the GI (gastrointestinal) tract called fistulas.
    • It is used with methotrexate to stop more problems in patients with moderate to very bad rheumatoid arthritis.
    • It is used to treat Crohn's disease. It may take 1 month to see the full effect.
    • It is used to treat arthritis.
    • It is used to treat very bad psoriasis.
    • It is used to treat ankylosing spondylitis.
    • It is used to treat ulcerative colitis.
    • It is an arthritis-changing drug. It lowers swelling and helps lower signs and protect joints from more harm.
    • It helps lower GI (gastrointestinal) swelling and other signs.


    How to take

    • You will need a TB (tuberculosis) test before starting this drug.
    • It is given as a shot into a vein over a period of time.



    • TB (tuberculosis) has been seen in patients started on this drug. These patients were exposed to TB in the past, but never got the infection. You will be tested to see if you have been exposed to TB before starting this drug.
    • This drug may add to your chance of getting lymphoma or other cancers.
    • Very bad infections have happened in patients who take this drug. Talk with the doctor.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.
    • Please read the medication guide.


    • If you have an allergy to infliximab or any other part of this drug.
    • If you are allergic to mouse proteins, talk with the doctor.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have a very weak heart.
    • If you are breast-feeding.


    • Very bad infections have been reported with use of this drug. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
    • Long-term use may raise your chance of cancer.
    • If you have heart disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have lung disease, talk with your doctor.
    • If you have MS (multiple sclerosis) or other nerve disease, talk with your doctor.
    • If you live where there is a high chance of some types of infections, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • Hepatitis B testing may be done. A hepatitis B infection may get worse during care.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
    • Fever, chills, itching, hives, chest pain or pressure, or shortness of breath when drug is given. Other drugs may be given to avoid these.
    • Headache.
    • Belly pain.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea).
    • Cough.
    • Harm to the liver may rarely happen.
    • In fistula patients, an abscess may rarely happen.

    Contact a healthcare provider

    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Signs of arthritis, fever, weight loss, chest pain or pressure, or shortness of breath if taking this drug for Crohn's disease.
    • Trouble breathing.
    • Swelling in your legs or belly.
    • Chest pain or pressure.
    • Not able to eat.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Very bad muscle pain or weakness.
    • Numbness or tingling in your hands or feet.
    • Feeling very tired or weak.
    • Very bad back pain.
    • Sudden change in eyesight.
    • Any bruising or bleeding.
    • Dark urine or yellow skin or eyes.
    • Night sweats.
    • A big weight gain.
    • A big weight loss.
    • Fever that does not go away.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

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    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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