Table of Contents > Drug > Clodronate Print

Clodronate

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: Canada: Bonefos®;Clasteon®

    Uses
    • It is used to treat high calcium levels.
    • Clodronate lowers bone loss.

    Dosing

    How to take

    • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
    • Oral:
    • Take with a full glass of water.
    • Swallow whole. Do not chew, break, or crush.
    • Bonefos®: Take on an empty stomach. Take 2 hours before or 2 hours after meals.
    • Clasteon®: Take on an empty stomach. Take 1 hour before or 1 hour after meals.
    • Shot:
    • It is given as a shot into a vein over a period of time.

    Missed Dose

    • Shot:
    • Call your doctor for an office visit.
    • Oral:
    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Oral:
    • Store at room temperature.
    • Protect capsules from water. Do not store in a bathroom or kitchen.
    • Shot:
    • This drug will be given to you in a hospital or doctor's office. You will not store it at home.

    Safety



    Avoid

    • If you have an allergy to clodronate or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Poor kidney function or stomach irritation.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • If you have kidney disease, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • Take good care of your teeth. See a dentist often.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Not hungry.
    • Loose stools (diarrhea).
    • Low calcium levels.
    • Bone, joint, or muscle pain may rarely happen.
    • A broken leg may rarely happen.
    • Harm to the jaw bone may rarely happen.
    • Shot:
    • Irritation where the shot is given.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain.
    • Trouble swallowing.
    • Very upset stomach or throwing up.
    • Very bad belly pain.
    • Very loose stools (diarrhea).
    • Jaw pain.
    • Very bad bone, joint, or muscle pain.
    • Very bad groin or thigh pain.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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