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Phentermine and Topiramate

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: QsymiaT

    Uses
    • It is used to treat obesity.
    • Phentermine and Topiramate act in the brain to help you eat less.

    Dosing

    How to take

    • Take early in the day to keep from having sleep problems.
    • Take with or without food.
    • Follow the diet and workout plan that your doctor told you about.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • You can only get this drug through the QysmiaT certified pharmacy network.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to phentermine, topiramate or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Glaucoma or overactive thyroid disease.
    • If you have taken isocarboxazid, phenelzine, or tranylcypromine in the last 14 days. Monoamine oxidase inhibitors (eg, isocarboxazid, phenelzine, and tranylcypromine) must be stopped 14 days before this drug is started. Taking both at the same time could cause risky high blood pressure.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • This drug may be habit-forming with long-term use.
    • If you have been taking this drug for many weeks, talk with your doctor before stopping. You may want to slowly stop this drug.
    • If you have high blood sugar (diabetes), talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have mental illness, talk with your doctor.
    • Have your blood pressure and heart rate checked often if you have heart disease.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with this drug may cause nervousness, shakiness, and a fast heartbeat.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Headache.
    • Hard stools (constipation).
    • Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
    • Not able to sleep.
    • Numbness and tingling.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of low mood (depression), thoughts of killing yourself, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
    • Change in thinking clearly and with logic.
    • Chest pain or pressure or a fast heartbeat.
    • Very bad dizziness or passing out.
    • Very nervous and excitable.
    • Very bad headache.
    • Sudden change in eyesight, eye pain, or irritation.
    • Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.
    • Not sweating during activities or in warm temperatures.
    • If seizures are new or worse after starting this drug.
    • For women, if you get pregnant while taking this drug.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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