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Vismodegib

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: ErivedgeT

    Uses
    • It is used to treat skin cancer.
    • Vismodegib harms cancer cells causing their death.

    Dosing

    How to take

    • If you are a woman of childbearing age, take a pregnancy test before starting this drug.
    • Take with or without food.
    • Swallow capsule whole. Do not chew, break, or crush.

    Missed Dose

    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not use 2 doses or extra doses.

    Storage

    • Store at room temperature. Do not freeze.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Do not take if you are pregnant. Use during pregnancy may cause birth defects. Use a helpful kind of birth control during care and for 7 months after stopping this drug. Men must also use birth control to protect their partners from becoming pregnant. If you get pregnant or plan on getting pregnant while taking this drug, call your doctor right away.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to vismodegib or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • Do not donate blood while using this drug and for 7 months after stopping.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Use birth control that you can trust to stop pregnancy while taking this drug.
    • If you are a man and have sex, protect your partner from pregnancy during care and for 2 months after stopping this drug. Use a latex condom even if you have had a vasectomy.

    Side Effects

    • Upset stomach or throwing up.
    • Hair loss. Hair most often grows back when this drug is stopped.
    • Hard stools (constipation).
    • Not hungry.
    • Feeling tired or weak.
    • Weight loss.
    • Loose stools (diarrhea).
    • Muscle or joint pain.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5F (38C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Very upset stomach or throwing up.
    • Very loose stools (diarrhea).
    • If you get pregnant while taking this drug.
    • For men, if your woman partner gets pregnant while you are being treated or within 7 months after stopping this drug.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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