Table of Contents > Drug > Ruxolitinib Print

Ruxolitinib

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: JakafiT
    • Brand Names: Canada: JakaviT

    Uses
    • It is used to treat myelofibrosis.

    Dosing

    How to take

    • Take as you have been told, even if you are feeling better.
    • Take with or without food. Always take with food or always take on an empty stomach.
    • Those who have feeding tubes may also use the tablet. Mix each tablet with 40 mL of water. Stir for 10 minutes. Give within 6 hours of mixing. Flush the feeding tube with water before and after this drug is given.

    Missed Dose

    • Never make up a missed dose. Skip the missed dose and go back to your normal time.
    • Do not use 2 doses or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

    Avoid

    • If you have an allergy to ruxolitinib or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are breast-feeding.

    Precautions

    • If you are being treated for any infection, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Dizziness.
    • Headache.
    • Bruising.
    • High cholesterol level.
    • Anemia, low white blood cell count, and low platelet count.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5F (38C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Very bad dizziness or passing out.
    • Very bad headache.
    • Trouble breathing.
    • Very upset stomach or throwing up.
    • Feeling very tired or weak.
    • Very bad belly pain.
    • Any bruising or bleeding.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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