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Related terms
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    Related terms
    • Brand Names: U.S.: Yervoy®
    • Brand Names: Canada: Yervoy®

    • It is used to treat skin cancer.
    • Ipilimumab helps fight cancer tumors.


    How to take

    • It is given as a shot into a vein over a period of time.



    • This drug may cause swelling of the bowels that may lead to tears or holes. Call your doctor if you have loose stools, blood in your stool, or very bad belly pain.
    • This drug may cause liver problems. Call your doctor if you see dark urine, feel tired, are not hungry, have an upset stomach, are throwing up, or have yellowing of the skin or eyes.
    • Very bad rashes have been reported. Talk with your doctor right away if you get a rash.
    • This drug may cause very bad nerve problems that may lead to not being able to move a part of the body (paralysis). Call your doctor if you have numbness, tingling, or weakness in your arms or legs.
    • This drug may change hormone levels in the body. Call your doctor if you have headaches, change in mood, dizziness, passing out, feeling cold, or weight gain.
    • Please read the medication guide.


    • If you have an allergy to ipilimumab or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are breast-feeding.


    • If you have an autoimmune disease such as rheumatoid arthritis or lupus, talk with your doctor.
    • If you have had a kidney transplant, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Feeling tired or weak.
    • Loose stools (diarrhea).
    • Upset stomach or throwing up.
    • Not hungry.
    • Itching.
    • Rash.

    Contact a healthcare provider

    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Very bad dizziness or passing out.
    • Numbness or tingling in your hands or feet.
    • Very bad headache.
    • Change in thinking clearly and with logic.
    • Feeling very tired or weak.
    • Very upset stomach or throwing up.
    • Very bad belly pain.
    • Dark urine or yellow skin or eyes.
    • Not able to eat.
    • Any bruising or bleeding.
    • Very loose stools (diarrhea).
    • Black, tarry, or bloody stools.
    • Very bad mouth irritation.
    • Very bad skin irritation.
    • Sudden change in eyesight.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
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    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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