Table of Contents > Drug > Tetrahydrocannabinol and Cannabidiol Print

Tetrahydrocannabinol and Cannabidiol

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: Canada: Sativex®

    Uses
    • It is used to treat pain in patients with MS (multiple sclerosis).
    • It is used to treat pain in patients with cancer.
    • Tetrahydrocannabinol and cannabidiol works in the brain to ease pain and spasms.

    Dosing

    How to take

    • Do not spray near an open flame.
    • Do not spray into nose.
    • Shake well before use.
    • Do not use spray if your mouth is sore.
    • Prime pump by squeezing it 2 to 3 times.
    • Spray into mouth below the tongue or on the inside of the cheeks.
    • Do not spray the back of the throat.
    • Move the site in your mouth with each spray.

    Missed Dose

    • Many times this drug is taken on an as needed basis.

    Storage

    • Store unopened vials in a refrigerator. Do not freeze.
    • Store opened 5.5 mL vials at room temperature. Throw away any part not used after 28 days.
    • Store opened 10 mL vials at room temperature. Throw away any part not used after 42 days.

    Safety



    Warnings

    • This drug may be habit-forming; avoid long-term use. Tell your doctor if you have a history of drug or alcohol abuse. This drug may cause unsafe heart-related side effects. Tell your doctor if you have any heart disease.
    • This drug may cause a fast heartbeat, blood pressure changes, dizziness, mood changes, or a change in thinking clearly and with logic.
    • Talk with your doctor if you have seizures or have ever had seizures.

    Avoid

    • If you have an allergy to tetrahydrocannabinol, cannabidiol, or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Heart disease or schizophrenia.
    • If you are a man with a sex partner who plans on getting pregnant at any time while you are being treated.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • This drug may be habit-forming with long-term use.
    • If you have a drug or drinking problem, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have seizures, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Use care to stop injury and avoid falls or crashes.
    • Avoid beer, wine, mixed drinks, or other drugs and natural products that slow your actions.
    • Use birth control that you can trust to stop pregnancy while taking this drug.

    Side Effects

    • Feeling lightheaded, sleepy, having blurred eyesight, or a change in thinking clearly. Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how this drug affects you.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Dry mouth. Good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help. See a dentist often.
    • Headache.
    • Mouth irritation.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Big change in balance.
    • Very bad dizziness or passing out.
    • Feeling very tired or weak.
    • Very upset stomach or throwing up.
    • Very bad mouth irritation.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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