Table of Contents > Drug > Certolizumab Pegol Print

Certolizumab Pegol

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Cimzia®
    • Brand Names: Canada: Cimzia®

    Uses
    • It is used to treat Crohn's disease.
    • It is used to treat rheumatoid arthritis.
    • It is an arthritis-changing drug. It lowers swelling and helps lower signs and protect joints from more harm.
    • It lowers the body's harmful response to diseases of the immune system.
    • It helps lower GI (gastrointestinal) swelling and other signs.

    Dosing

    How to take

    • You will need a TB (tuberculosis) test before starting this drug.
    • It is given as a shot into the fatty part of the skin.
    • Your doctor may teach you how to give the shot.
    • Follow how to give closely if you or a family member is giving the shot at home.
    • Before giving the shot, bring it to room temperature.
    • Wash your hands before and after use.
    • Move the site where you give the shot with each shot.
    • Throw syringe away after use. Do not use more than one time.
    • Throw away needles in a needle/sharp disposal box and take the box back to your doctor when it is full.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.

    Storage

    • Store in a refrigerator. Do not freeze.
    • Protect from light.

    Safety



    Warnings

    • TB (tuberculosis) has been seen in patients started on this drug. These patients were exposed to TB in the past, but never got the infection. You will be tested to see if you have been exposed to TB before starting this drug.
    • This drug may add to your chance of getting lymphoma or other cancers.
    • Very bad infections have happened in patients who take this drug. Talk with the doctor.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to certolizumab pegol or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are breast-feeding.

    Precautions

    • Hepatitis B testing may be done. A hepatitis B infection may get worse during care.
    • Long-term use may raise your chance of cancer.
    • Very bad infections have been reported with use of this drug. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
    • If you have cancer, talk with your doctor.
    • If you have high blood sugar (diabetes), talk with your doctor. You may be more likely to get infections.
    • If you have heart disease, talk with your doctor.
    • If you have MS (multiple sclerosis) or other nerve disease, talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • Tell your doctor if you are pregnant or plan on getting pregnant.

    Side Effects

    • Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
    • Headache.
    • Runny nose.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Irritation where the shot is given.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Trouble breathing.
    • Chest pain or pressure.
    • Very bad dizziness.
    • Very bad headache.
    • Very bad belly pain.
    • Very upset stomach or throwing up.
    • Sudden change in eyesight.
    • Numbness or tingling in your hands or feet.
    • Very bad swelling or pain of hands or feet.
    • Any bruising or bleeding.
    • Very bad joint pain.
    • Very bad back pain.
    • Dark urine or yellow skin or eyes.
    • A big weight loss.
    • Night sweats.
    • Fever that does not go away.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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