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Travelers' Diarrhea and Cholera Vaccine


Related terms
Author information


    Related terms
    • Brand Names: Canada: Dukoral®

    • It is used to stop travelers' diarrhea and cholera.
    • Travelers' diarrhea and cholera vaccine helps the body fight infection and protects the body from travelers' diarrhea and cholera.


    How to take

    • Take on an empty stomach. Take 1 hour before or 1 hour after meals.
    • Melt 1 packet in 5 ounces of water.
    • Do not mix with juice, milk, or other drinks.
    • Shake vaccine liquid and add to the mixture. Mix well and drink.
    • Take the last dose at least 1 week before you travel to the high risk place.


    • Store in a refrigerator. Do not freeze.
    • After mixing, you may store at room temperature for 2 hours.
    • Drink within 2 hours of mixing.



    • If you have an allergy to travelers' diarrhea and cholera vaccine or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have a latex allergy, talk with your doctor.


    • This drug does not give 100% protection. You must still follow steps to protect the body from travelers' diarrhea and cholera. Talk with the doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • All bad side effects to this vaccine must be reported to the Senior Product Safety Officer, Aventis Pasteur Limited. Ask your doctor to file the report. You may also call to file a report at 1-888-621-1146.
    • Belly pain.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea).
    • Unsafe allergic effects may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad belly pain.
    • Very loose stools (diarrhea).
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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