Table of Contents > Drug > Lenalidomide Print

Lenalidomide

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Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Revlimid®
    • Brand Names: Canada: Revlimid®

    Uses
    • It is used to treat cancer.
    • Lenalidomide harms cancer cells causing their death.

    Dosing

    How to take

    • Take this drug at the same time of day.
    • Take with or without food. Take with food if it causes an upset stomach.
    • Take with a full glass of water.
    • Swallow whole. Do not chew, break, or crush.
    • If you are a woman of childbearing age, pregnancy tests will be given before starting this drug, while you are on this drug, and for 4 weeks after you have stopped this drug.

    Missed Dose

    • If it has been less than 12 hours since a normal dose, take a missed dose as soon as you think about it and go back to your normal time.
    • If it has been 12 hours or more since the missed dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • Do not take if you are pregnant. Use during pregnancy may cause birth defects. Women must use 2 helpful kinds of birth control during care. A man must use a latex condom even if he has had a vasectomy. A written explanation of the risks must be presented, read, and signed by the patient before getting this drug. If a patient is younger than 18 years of age, this written warning must be signed by a parent or legal guardian.
    • Unsafe blood cell count problems may happen. Report any fever, sore throat, mouth sores, infections, easy bruising, or purple "splotches" on your skin to your doctor right away.
    • This drug may cause blood clots in your veins or lungs. Call your doctor right away if you have any chest pain, shortness of breath, or pain or swelling of the legs or arms.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.
    • Please read the medication guide.

    Avoid

    • If you have an allergy to lenalidomide or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you are of childbearing age, but are not using 2 kinds of birth control or if you are planning to get pregnant during your care or within 4 weeks after care has ended.
    • If you are pregnant or may be pregnant.
    • If you are breast-feeding.

    Precautions

    • If you have a blood clotting problem, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you are on a lactose-free diet, talk with your doctor.
    • Have your blood work checked. Talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with your doctor before getting any vaccines. Use with this drug may either raise the chance of an infection or make the vaccine not work as well.
    • Talk with your doctor before using products that have aspirin, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain drugs, or vitamin E.
    • Use 2 kinds of birth control that you can trust before care begins, during care, and for 4 weeks after care ends.
    • If you are a man and have sex, protect your partner from pregnancy. Use a latex condom.
    • Do not donate blood while using this drug and for 1 month after stopping.
    • If you are a man, do not donate sperm while using this drug and for 1 month after stopping.

    Side Effects

    • Chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
    • Anemia, low white blood cell count, and low platelet count.
    • Back pain.
    • Belly pain.
    • Blurred eyesight. Use care when driving or doing other tasks that call for clear eyesight.
    • Cough.
    • Loose stools (diarrhea).
    • Headache.
    • Itching.
    • Joint pain.
    • Muscle weakness.
    • Rash.
    • Feeling tired or weak.
    • Feeling dizzy. Rise slowly over a few minutes when sitting or lying down. Be careful climbing.
    • Hard stools (constipation). Drinking more liquids, working out, or adding fiber to your diet may help. Talk with your doctor about a stool softener or laxative.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Swelling in the arms or legs.
    • Other kinds of cancer may rarely happen later in life.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Signs of infection. These include a fever of 100.5°F (38°C) or higher, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, wound that will not heal, or anal itching or pain.
    • Chest pain or pressure.
    • Trouble breathing.
    • Swelling, warmth, or pain in the leg or arm.
    • Very upset stomach or throwing up.
    • Very loose stools (diarrhea).
    • Any bruising or bleeding.
    • Feeling very tired or weak.
    • For women, if you get pregnant while taking this drug.
    • Very bad skin irritation.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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