Table of Contents > Drug > Deferasirox Print

Deferasirox

Image

Notes
Related terms
Uses
Dosing
Safety
Author information

Notes

    Related terms
    • Brand Names: U.S.: Exjade®
    • Brand Names: Canada: Exjade®

    Uses
    • It is used to get rid of iron when too much is in the body.
    • Deferasirox binds to iron and gets rid of it from the body.

    Dosing

    How to take

    • Take this drug at the same time of day.
    • Take on an empty stomach. Take 30 minutes before a meal.
    • Mix the tablet with fruit juice (orange, apple) or water until melted and drink right away. Do not chew or swallow it whole.
    • After drinking, rinse the rest of the drug in the glass with more juice or water and drink.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.

    Storage

    • Store at room temperature.
    • Protect from water. Do not store in a bathroom or kitchen.

    Safety



    Warnings

    • This drug may cause very bad kidney and/or liver problems.
    • This drug may raise the chance of bleeding from the stomach or bowel.
    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.

    Avoid

    • If you have an allergy to deferasirox or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Very bad kidney disease, very bad liver disease, or low platelets.

    Precautions

    • If you have kidney disease, talk with your doctor.
    • If you have liver disease, talk with your doctor.
    • If you have had an ulcer or bleeding from your stomach or bowel, talk with your doctor.
    • Have your blood work checked often. Talk with your doctor.
    • Have your eye pressure checked. Talk with your doctor.
    • Have an eye exam before starting care and then one every year.
    • Have a hearing test before starting this drug and then every year.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Do not take antacids with this drug.
    • Talk with your doctor before using products that have aspirin, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain drugs, or vitamin E.
    • You may not be alert. Avoid driving and doing other tasks or actions until you see how this drug affects you.
    • Avoid beer, wine, or mixed drinks.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Fever.
    • Headache.
    • Belly pain.
    • Cough.
    • Runny nose.
    • Sore throat.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea).
    • Kidney function that gets worse may rarely happen.
    • Harm to the liver may rarely happen.
    • Very bad bleeding may rarely happen.
    • Change in hearing may rarely happen.
    • Eye problems may rarely happen.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very upset stomach or throwing up.
    • Very loose stools (diarrhea).
    • Hearing loss.
    • Sudden change in eyesight, eye pain, or irritation.
    • Not able to eat.
    • Dark urine or yellow skin or eyes.
    • Feeling very tired or weak.
    • Any bruising or bleeding.
    • Black, tarry, or bloody stools.
    • Not able to pass urine.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)


    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

    Search Site